Facial polynucleotides for your skin quality
Treatments with polynucleotides to regenerate the skin and improve its quality with maximum precision and naturalness.

Treatment duration:
30 and 45 minutes
With EcoDerm NESAI® ultrasound
To consider
Premium quality
IdB Seal
What is the polynucleotide treatment?
The polynucleotide treatment is a medical-aesthetic procedure aimed at regenerating, repairing, and improving skin quality from within, acting at the cellular level to restore its structure, hydration, and elasticity.
It is not a filler or a change of features, but a regenerative treatment that stimulates the skin's natural mechanisms, progressively improving texture, luminosity, firmness, and skin health.
Polynucleotides promote tissue repair, collagen production, and cellular regeneration, achieving stronger, more hydrated, and visibly more luminous skin.
Types of polynucleotide treatments
Facial regenerative polynucleotides
Focused on improving the overall quality of facial skin, increasing deep hydration, elasticity, and luminosity, and preventing or correcting the first signs of aging.

Polynucleotides for eye contour
Designed to treat one of the most delicate areas: dark circles, thin skin, dehydration, and small wrinkles, improving the texture and quality of the skin without adding volume.

Body polynucleotides or specific areas
Indicated for neck, décolleté, hands, or other areas with loss of skin quality, sagging, or sun damage, improving the structure and firmness of the skin.

What is the polynucleotide treatment like?
The polynucleotide treatment is performed in a medical consultation, without the need for an operating room or general anesthesia. It is a minimally invasive procedure, carried out under strict medical protocols and with professional supervision at all times, ensuring maximum safety for the patient.
Initial assessment

The first step is a specialized medical consultation with the doctor who will perform the treatment. During this visit, the actual condition of your skin is analyzed, your aesthetic goals are discussed, and a fully personalized plan is designed. To book the appointment, a payment of €50 must be made in advance.
Advanced viability analysis

During the consultation, skin quality, hydration, elasticity, texture, and degree of aging are evaluated to determine if you are a candidate for the treatment and to define the most appropriate protocol according to your real needs.
Treatment application

The treatment with polynucleotides is performed in a medical consultation, through superficial microinjections.
It is a quick, minimally invasive, and well-tolerated procedure, usually lasting between 30 and 45 minutes.
Start looking how you want to feel.

The results appear progressively and naturally, improving skin quality from the inside: more hydration, more luminosity, more firmness, and visibly healthier skin.
What is the price of the polynucleotides treatment?
The treatment with polynucleotides is completely personalized, so there is no single standard price. At the Instituto de Benito, each plan is designed taking into account the specific characteristics of the skin, the patient's aesthetic goals, and the areas to be treated.
Are you suitable for a polynucleotides treatment?
The treatment with polynucleotides is indicated for people who want to improve their skin quality, regenerate it from the inside, and prevent or treat signs of aging when the skin has lost hydration, firmness, elasticity, or luminosity.
- 01
Your skin is dull, dehydrated, or has lost quality
When the skin loses hydration and density, its appearance becomes dull, lacking luminosity, and with an uneven texture.
- 02
You notice a lack of firmness or elasticity
Over time, the skin loses collagen and elasticity, becoming more flaccid and less resilient.
- 03
You have thin, sensitive, or sun-damaged skin or due to aging
Thin or sensitized skin is more vulnerable to aging and external damage. Polynucleotides strengthen the skin's structure, improve its resilience, and promote its repair.
- 04
You want to prevent or treat the first signs of aging
This treatment is ideal for both prevention and correction of the first signs of aging.
- 05
You are looking for a treatment that improves the skin
Polynucleotides do not fill or alter features.
- 06
You desire natural, progressive results with a medical basis
This is a biological and regenerative treatment, whose results appear gradually and elegantly

Our medical group facial aesthetic medicine
The Instituto de Benito is a benchmark in aesthetic medicine treatments.
Our team combines medical excellence, maximum technical precision, and a human and personalized approach, ensuring safe, effective treatments aimed at achieving natural, harmonious, and coherent results with each person's identity.




Commitment to aesthetic medicine
At Instituto de Benito, the health of your skin is our top priority. Every patient who begins a bio-stimulation treatment with polynucleotides undergoes a thorough diagnostic evaluation and personalized follow-up, allowing us to optimize cell regeneration results and ensure tissue response.
Where to get the Polynucleotides treatment
Related treatments
Frequently asked questions about Polynucleotides
What results can I expect?
More hydrated, luminous skin with better quality and texture. Polynucleotides stimulate cell regeneration from within, progressively improving the elasticity and overall appearance of the skin. Results begin to be noticeable within a few weeks and progressively improve after each session.
Does the polynucleotide treatment hurt?
It is a well-tolerated treatment. It may cause slight discomfort during application, but it is usually performed with topical anesthesia for greater comfort.
How long do the results last?
The effects are progressive and cumulative. Depending on the skin type and the applied protocol, results can last between 6 and 12 months, with maintenance sessions being recommended.
What are the risks of polynucleotide treatment?
It is a safe treatment when performed in specialized centers and by qualified medical professionals. However, like any medical-aesthetic procedure, it may present mild side effects.
At the Instituto de Benito, all treatments are carried out under strict medical protocols to maximize safety and minimize any risk.
Most common side effects (mild and temporary)
- Redness or slight swelling in the treated area, which disappears in a few hours or days.
- Small bruises at the injection points.
- Small papules in the treated area that are quickly reabsorbed.
Uncommon effects
- More intense or persistent inflammatory reaction.
- Local infection (very rare, thanks to aseptic measures).
- Allergic reaction to the product or any component (exceptional).
How many sessions are necessary?
It is common to carry out an initial protocol to assess the sessions, spaced several weeks apart, and subsequently maintenance sessions according to the skin's needs.
When can the results be seen?
The skin begins to improve from the first weeks, but the most visible results are progressively appreciated over 1 to 3 months, as cell regeneration is stimulated.
Can I resume normal life after the treatment?
Yes. You can resume your daily routine immediately, avoiding exercise, sauna, no makeup, not touching the area, or direct sun exposure during the first 24-48 hours.
Can I combine polynucleotides with other treatments?
Yes. It is a treatment that can be perfectly combined with other procedures such as hyaluronic acid, laser, fractional radiofrequency, or botulinum toxin, always under medical evaluation.
What happens if my skin ages or I change habits?
Aging continues naturally, but polynucleotides help improve skin quality and slow down its signs. Maintaining healthy habits and good skin care prolongs the results.








